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Masoud RANJBARNIA, Milad ZAHERI, Daniel DIAS
《结构与土木工程前沿(英文)》 2020年 第14卷 第4期 页码 998-1011 doi: 10.1007/s11709-020-0621-8
关键词: urban tunnel sprayed concrete reverse fault normal fault finite difference analysis
Genomic variations in the counterpart normal controls of lung squamous cell carcinomas
null
《医学前沿(英文)》 2018年 第12卷 第3期 页码 280-288 doi: 10.1007/s11684-017-0580-1
Lung squamous cell carcinoma (LUSC) causes approximately 400 000 deaths each year worldwide. The occurrence of LUSC is attributed to exposure to cigarette smoke, which induces the development of numerous genomic abnormalities. However, few studies have investigated the genomic variations that occur only in normal tissues that have been similarly exposed to tobacco smoke as tumor tissues. In this study, we sequenced the whole genomes of three normal lung tissue samples and their paired adjacent squamous cell carcinomas. We then called genomic variations specific to the normal lung tissues through filtering the genomic sequence of the normal lung tissues against that of the paired tumors, the reference human genome, the dbSNP138 common germline variants, and the variations derived from sequencing artifacts. To expand these observations, the whole exome sequences of 478 counterpart normal controls (CNCs) and paired LUSCs of The Cancer Genome Atlas (TCGA) dataset were analyzed. Sixteen genomic variations were called in the three normal lung tissues. These variations were confirmed by Sanger capillary sequencing. A mean of 0.5661 exonic variations/Mb and 7.7887 altered genes per sample were identified in the CNC genome sequences of TCGA. In these CNCs, C:G→T:A transitions, which are the genomic signatures of tobacco carcinogen N-methyl-N-nitro-N-nitrosoguanidine, were the predominant nucleotide changes. Twenty five genes in CNCs had a variation rate that exceeded 2%, including ARSD (18.62%), MUC4 (8.79%), and RBMX (7.11%). CNC variations in CTAGE5 and USP17L7 were associated with the poor prognosis of patients with LUSC. Our results uncovered previously unreported genomic variations in CNCs, rather than LUSCs, that may be involved in the development of LUSC.
关键词: lung cancer counterpart normal control genomic variations
Rahul SHARMA,Sathans SUHAG
《能源前沿(英文)》 2020年 第14卷 第2期 页码 400-409 doi: 10.1007/s11708-017-0459-5
关键词: PV system grid interface feedback linearization inverter LCL filter
Dynamic in-plane transversal normal stresses in the concrete face of CFRD
Neftalí SARMIENTO-SOLANO, Miguel P. ROMO
《结构与土木工程前沿(英文)》 2019年 第13卷 第1期 页码 135-148 doi: 10.1007/s11709-018-0481-7
关键词: CFR dams dynamic analysis in-plane normal stresses concrete face
李德毅,刘常昱
《中国工程科学》 2004年 第6卷 第8期 页码 28-34
分布函数是分析随机现象的重要工具,正态分布是最重要的概率分布,在自然科学和社会科学中应用广泛;隶属函数是模糊集合的基石,正态隶属函数也有广泛的应用。但是,精确确定一个模糊概念的隶属函数已经成为模糊学应用的瓶颈。云模型把随机性和模糊性结合起来,用数字特征熵,揭示随机性与模糊性的关联性,并用来表示一个定性概念的粒度。正态云模型通过期望、熵和超熵构成的特定结构发生器,生成定性概念的定量转换值,体现概念的不确定性。这种特定结构不但放宽了形成正态分布的前提条件,而且把精确确定隶属函数放宽到构造正态隶属度分布的期望函数,因而更具有普遍适用性,更简单、直接地完成了定性与定量之间的相互转换过程。
李德毅,刘常昱,淦文燕
《中国工程科学》 2011年 第13卷 第4期 页码 20-23
正态分布和重尾分布在概率研究中具有非常重要的地位,二者具有完全不同的数学形式和物理意义。正态分布的密度函数以指数函数衰减至0,服从正态分布的随机变量,其绝大多数取值在其期望附近,偏离期望很大的取值很少。而服从重尾分布的随机变量,其尾分布函数具有重尾特性,密度函数以幂指数衰减至0。笔者证明了正态云模型是具有均值的重尾分布,是介于正态分布与重尾分布之间的中间状态,正态云模型的参数超熵He是可以实现正态分布向重尾分布转换的桥梁。
Modeling and simulation of normal and hemiparetic gait
Lely A. LUENGAS,Esperanza CAMARGO,Giovanni SANCHEZ
《机械工程前沿(英文)》 2015年 第10卷 第3期 页码 233-241 doi: 10.1007/s11465-015-0343-0
Gait is the collective term for the two types of bipedal locomotion, walking and running. This paper is focused on walking. The analysis of human gait is of interest to many different disciplines, including biomechanics, human-movement science, rehabilitation and medicine in general. Here we present a new model that is capable of reproducing the properties of walking, normal and pathological. The aim of this paper is to establish the biomechanical principles that underlie human walking by using Lagrange method. The constraint forces of Rayleigh dissipation function, through which to consider the effect on the tissues in the gait, are included. Depending on the value of the factor present in the Rayleigh dissipation function, both normal and pathological gait can be simulated. First of all, we apply it in the normal gait and then in the permanent hemiparetic gait. Anthropometric data of adult person are used by simulation, and it is possible to use anthropometric data for children but is necessary to consider existing table of anthropometric data. Validation of these models includes simulations of passive dynamic gait that walk on level ground. The dynamic walking approach provides a new perspective of gait analysis, focusing on the kinematics and kinetics of gait. There have been studies and simulations to show normal human gait, but few of them have focused on abnormal, especially hemiparetic gait. Quantitative comparisons of the model predictions with gait measurements show that the model can reproduce the significant characteristics of normal gait.
关键词: bipedal gait biomechanics dynamic walking gait model human gait hemiparetic human gait
基于鲁棒法矢滤波和交替顶点更新的有效网格去噪 Article
Tao LI, Jun WANG, Hao LIU, Li-gang LIU
《信息与电子工程前沿(英文)》 2017年 第18卷 第11期 页码 1828-1842 doi: 10.1631/FITEE.1601229
Empirical models and design codes in prediction of modulus of elasticity of concrete
Behnam VAKHSHOURI, Shami NEJADI
《结构与土木工程前沿(英文)》 2019年 第13卷 第1期 页码 38-48 doi: 10.1007/s11709-018-0479-1
关键词: modulus of elasticity normal strength normal weight concrete empirical models design codes compressive strength density
Basic research on machinery fault diagnostics: Past, present, and future trends
Xuefeng CHEN, Shibin WANG, Baijie QIAO, Qiang CHEN
《机械工程前沿(英文)》 2018年 第13卷 第2期 页码 264-291 doi: 10.1007/s11465-018-0472-3
Machinery fault diagnosis has progressed over the past decades with the evolution of machineries in terms of complexity and scale. High-value machineries require condition monitoring and fault diagnosis to guarantee their designed functions and performance throughout their lifetime. Research on machinery Fault diagnostics has grown rapidly in recent years. This paper attempts to summarize and review the recent R&D trends in the basic research field of machinery fault diagnosis in terms of four main aspects: Fault mechanism, sensor technique and signal acquisition, signal processing, and intelligent diagnostics. The review discusses the special contributions of Chinese scholars to machinery fault diagnostics. On the basis of the review of basic theory of machinery fault diagnosis and its practical applications in engineering, the paper concludes with a brief discussion on the future trends and challenges in machinery fault diagnosis.
关键词: fault diagnosis fault mechanism feature extraction signal processing intelligent diagnostics
Machine learning for fault diagnosis of high-speed train traction systems: A review
《工程管理前沿(英文)》 doi: 10.1007/s42524-023-0256-2
关键词: high-speed train traction systems machine learning fault diagnosis
Acoustic fault signal extraction via the line-defect phononic crystals
《机械工程前沿(英文)》 2022年 第17卷 第1期 页码 10-10 doi: 10.1007/s11465-021-0666-y
关键词: phononic crystals line-defect fault signal extraction acoustic enhancement
Iterative HOEO fusion strategy: a promising tool for enhancing bearing fault feature
《机械工程前沿(英文)》 2023年 第18卷 第1期 doi: 10.1007/s11465-022-0725-z
关键词: higher order energy operator fault diagnosis manifold learning rolling element bearing information fusion
Zhenyun DUAN, Houjun CHEN, Zhilan JU, Jian LIU
《机械工程前沿(英文)》 2012年 第7卷 第3期 页码 312-321 doi: 10.1007/s11465-012-0308-5
In this paper, loxodromic-type normal circular-arc spiral bevel gear is proposed as a novel application of the circular-arc tooth profile at the gear transmission with intersecting axes. Based on the principle of molding-surface conjugation, the study develops a mathematical model for the tooth alignment curve and the computational flow at the design stage to enable the generation of the tooth surface. Machining of the tooth surface is then carried out to determine the interference-free tool path of the numerical control (NC). Moreover, a pair of loxodromic-type normal circular-arc spiral bevel gears is manufactured on computer numerical control (CNC) machine tools. The proposed theory and method are experimentally investigated, and the obtained results primarily reflect the superior performance of the proposed novel gear.
关键词: loxodrome circular-arc tooth profile Wildhaber-Novikov (W-N) gear spiral bevel gear
《机械工程前沿(英文)》 2021年 第16卷 第4期 页码 814-828 doi: 10.1007/s11465-021-0650-6
关键词: bearing cross-severity fault diagnosis hierarchical fault diagnosis convolutional neural network decision tree
标题 作者 时间 类型 操作
Three-dimensional finite difference analysis of shallow sprayed concrete tunnels crossing a reverse faultor a normal fault: A parametric study
Masoud RANJBARNIA, Milad ZAHERI, Daniel DIAS
期刊论文
Feedback linearization based control for weak grid connected PV system under normal and abnormal conditions
Rahul SHARMA,Sathans SUHAG
期刊论文
Dynamic in-plane transversal normal stresses in the concrete face of CFRD
Neftalí SARMIENTO-SOLANO, Miguel P. ROMO
期刊论文
Modeling and simulation of normal and hemiparetic gait
Lely A. LUENGAS,Esperanza CAMARGO,Giovanni SANCHEZ
期刊论文
Empirical models and design codes in prediction of modulus of elasticity of concrete
Behnam VAKHSHOURI, Shami NEJADI
期刊论文
Basic research on machinery fault diagnostics: Past, present, and future trends
Xuefeng CHEN, Shibin WANG, Baijie QIAO, Qiang CHEN
期刊论文
Mathematical model and manufacture programming of loxodromic-type normal circular-arc spiral bevel gear
Zhenyun DUAN, Houjun CHEN, Zhilan JU, Jian LIU
期刊论文